Signs | Spastic paraparesis, cerebellar signs ± optic atrophy in young female |
Differential diagnosis | Demyelinating disease |
Tests |
Vitamin B12 to exclude subacute degeneration
MR brain - hyperintense focal perventricular white matter lesions on T2 weighted Lumbar puncture - raised total protein, oligoclonal bands Serum electrophoresis - to exclude oligoclonal bands in serum |